Resources On Call

Resources On Call is the pioneer in virtual concierge services that enhance a company's bottom line, keeping employees engaged and productive at work. Founded in 1995, ROC meets thousands of requests each year: • Childcare & summer camps • Eldercare • Doctors & dentists • College advisors & financial aid • House cleaners • Handy men • Pet care • Apartments & movers • Legal & financial • And much more We are not self-service – We are personal service. We are high touch, but not high price. Contact us today to improve your company's bottom line.

Coronado Biosciences

Coronado is a biopharmaceutical company focused on novel immunotherapy agents for cancer and inflammatory diseases. Coronado's two principal pharmaceutical product candidates are initially targeted for clinical development for inflammatory bowel disease, multiple sclerosis and acute myeloid leukemia. In November 2007, Coronado acquired from UCL Business PLC, an affiliate of University College London ("UCLB"), exclusive worldwide rights to develop and market CNDO-109, a compound that activates the natural killer ("NK") cells (known as Tumor Activated NK cells) of the host immune system to seek and destroy cancer cells, for the treatment of cancer. When activated, NK cells have the ability to differentiate between normal cells and cancer cells, and kill cancer cells by granzyme mediated lysis, a biochemical process whereby the NK cells directly kill cancer cells by destroying their cell structures. CNDO-109 has the potential to benefit patients with a wide variety of hematologic and solid cancers as data obtained from in vitro and in vivo preclinical studies of the product candidate conducted by UCL have demonstrated that CNDO-109 activated NK cells directly kill cells that cause hematologic malignancies including myeloid leukemia, multiple myeloma ("MM"), breast, prostate and ovarian cancers.

DeuteRx

Formed in 2012, DeuteRx is a virtual biopharmaceutical company focused on improving racemic drugs for patients. Our team has pioneered the use of Deuterium-Enabled Chiral Switching (DECS) to isolate a single stereoisomer from a mixture of interconverting stereoisomers. DECS is a revolutionary strategy that stabilizes the preferred stereoisomer in existing drugs sold as racemic mixtures to reduce deleterious side-effects and improve efficacy. Numerous drugs are still developed and marketed as racemic mixtures because their stereoisomers chemically interconvert in vivo. The development of the single, preferred stereoisomer from the parent racemic drug, also known as a 'chiral switch,' often leads to drugs with superior therapeutic properties. Replacing the exchangeable hydrogen at the chiral center with deuterium enables stabilization and characterization of the single, preferred stereoisomer with a new composition of matter patent protection and an expedited path to market. We have applied DECS to a wide range of clinical therapies, including deuterium-stabilized S-bupropion, for neurological disorders (NTY-184 at Neuromity in 2021), deuterium-stabilized R-pioglitazone for nonalcoholic steatohepatitis (NASH) (PXL065, acquired by Poxel in 2018) and deuterium-stabilized S-lenalidomide (DRX-053, acquired by Celgene in 2012).

Fluotics

Fluotics manufactures and distributes robotic pipette tips for industry standard liquid handlers such as the Beckman Biomek FX/NX, Agilent Vprep/Bravo, Tecan Freedom Evo/Fluent, Perkin Elmer Janus/EP3, and Analytik Jena Cybio Felix/Well. Fluotics has customers around the world ranging from pharmaceuticals and biotech companies to academic centers. For more information contact: [email protected]

Prime Photonics LC

Prime Photonics develops and delivers extreme environment sensor, materials and energy harvesting products that enable next generation military and commercial capabilities in test and measurement, controls, and health monitoring applications. Prime Photonics is located in Blacksburg, VA, just a few miles from the campus of Virginia Tech. Founded in 1999, Prime Photonics is a company focused on bringing innovative products to the marketplace while closely adhering to our Guiding Principles of Integrity, Commitment to Stakeholders and Performance.