 | Aiken Regional Medical Centers | Aiken, south carolina, united states | 520 | hospital and health care | 1917 | |
 | columbia vehicles | aiken, south carolina, united states | 56 | motor vehicle manufacturing | 1947 | |
 | Security Federal Bank | Aiken, south carolina, united states | 160 | banking | 1922 | |
 | Houndslake Country Club | Aiken, south carolina, united states | 20 | hospitality | 1974 | |
 | Trophies Unlimited | Aiken, south carolina, united states | 12 | retail | 1977 | |
 | Savannah River Nuclear Solutions | aiken, south carolina, united states | 2.8K | government relations services | 2008 | |
 | RPM Productions, Inc. | Aiken, south carolina, united states | 6 | entertainment | 1980 | |
 | South Aiken Chiropractic | Aiken, south carolina, united states | 3 | government administration | - | |
 | Aiken Chamber of Commerce | Aiken, south carolina, united states | 11 | civic and social organization | 1918 | |
 | cb&i areva mox services, llc | aiken, south carolina, united states | 202 | construction | - | |
| Utility Products International LLC | Aiken, south carolina, united states | 1 | appliances, electrical, and electronics manufacturing | 2018 | |
 | WingPlace | Aiken, south carolina, united states | 9 | restaurants | 2006 | |
 | Impact Ministries International, Inc. | Aiken, south carolina, united states | 4 | religious institutions | 2001 | |
 | Carver Security Systems, Inc. | Aiken, south carolina, united states | 6 | security and investigations | 1991 | |
 | Freitas Wealth Management Group | Aiken, south carolina, united states | 1 | financial services | 2014 | |
| Churchill Commons Apartments | Aiken, south carolina, united states | 3 | publishing | - | |
| Howitzer Consulting, LLC | Aiken, south carolina, united states | 8 | information technology and services | - | |
| Aiken Industries Inc | Aiken, south carolina, united states | 6 | apparel and fashion | - | |
 | Aiken Council of the International Reading Association | Aiken, south carolina, united states | 6 | primary and secondary education | - | |
 | Hoof Pix® Sport Horse Photography, LLC | Aiken, south carolina, united states | 2 | photography | 1992 | |
