 | Mid Florida Cancer Centers | Orange City, florida, united states | 23 | hospital and health care | - | |
 | Blackwell, CPA | Orange City, florida, united states | 1 | accounting | - | |
 | Deploy Tech Services | Orange City, florida, united states | 3 | information technology and services | 2003 | |
 | Dollar Store Brokerage, LLC | Orange City, florida, united states | 1 | real estate | 2017 | |
 | University High School | Orange City, florida, united states | 3 | - | - | |
 | 866 SaniClean | Orange City, florida, united states | 3 | retail | 1979 | |
 | Bizcard Xpress of Orange City | Orange City, florida, united states | - | printing | 2009 | |
 | VICTORY QUICK LUBE, INC. | Orange City, florida, united states | - | individual and family services | - | |
 | florida orthopaedic assoc | orange city, florida, united states | - | hospital and health care | - | |
| Orange City Jewelers | Orange City, florida, united states | - | retail | - | |
 | orange city fire department | orange city, florida, united states | - | public safety | 1882 | |
| global servants | orange city, florida, united states | - | non-profit organizations | 1977 | |
| aging tree, llc | orange city, florida, united states | - | consumer services | 2013 | |
 | NORA B. ROMERO, CPA, LLC | Orange City, florida, united states | - | - | - | |
| faith life international church | orange city, florida, united states | - | religious institutions | 2005 | |
| lake mary pediatrics | orange city, florida, united states | - | medical practice | - | |
 | total sleep management | orange city, florida, united states | - | hospital and health care | 2002 | |
| sona imaging solutions, inc. | orange city, florida, united states | - | medical practice | 2008 | |
 | central florida pediatrics | orange city, florida, united states | - | medical practice | - | |
| simply scrubs of florida, inc. | orange city, florida, united states | - | apparel and fashion | 2011 | |
